Read it through once

For instance, when the Mississippi was first seen by a white man, less than a quarter of a century had elapsed since Francis I.'s defeat at Pavia; the death of Raphael; the death of Bayard, _Sans Peur Et Sans Reproche_; the driving out of the Knights-Hospitallers from Rhodes by the Turks; and the placarding of the Ninety-Five Propositions,--the act which began the Reformation. When De Soto took his glimpse of the river, Ignatius Loyola was an obscure name; the order of the Jesuits was not yet a year old; Michael Angelo's paint was not yet dry on the Last Judgment in the Sistine Chapel; Mary Queen of Scots was not yet born, but would be before the year closed. Catherine de Medici was a child; Elizabeth of England was not yet in her teens; Calvin, Benvenuto Cellini, and the Emperor Charles V. were at the top of their fame, and each was manufacturing history after his own peculiar fashion; Margaret of Navarre was writing the 'Heptameron' and some religious books,--the first survives, the others are forgotten, wit and indelicacy being sometimes better literature preservers than holiness; lax court morals and the absurd chivalry business were in full feather, and the joust and the tournament were the frequent pastime of titled fine gentlemen who could fight better than they could spell, while religion was the passion of their ladies, and classifying their offspring into children of full rank and children by brevet their pastime.